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Comment
. 2017 Nov 21;47(5):810-812.
doi: 10.1016/j.immuni.2017.10.010.

The Silent Undertakers: Macrophages Programmed for Efferocytosis

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The Silent Undertakers: Macrophages Programmed for Efferocytosis

Judith E Allen et al. Immunity. .
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Abstract

Two recent Immunity papers provide new insight into efferocytosis by tissue-resident macrophages. Baratin et al. (2017) identify a resident macrophage population in the T cell zone of lymph nodes responsible for the silent uptake of vast numbers of apoptotic cells. Roberts et al. (2017) find that resident macrophages can be programmed by local tissue signals not to respond to the nucleic acid of apoptotic cells.

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