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Review
. 2018 Jan 24;56(2):e01588-17.
doi: 10.1128/JCM.01588-17. Print 2018 Feb.

Candida auris: an Emerging Fungal Pathogen

Emily S Spivak  1 , Kimberly E Hanson  2   3
Affiliations
Review

Candida auris: an Emerging Fungal Pathogen

Emily S Spivak et al. J Clin Microbiol. .

Abstract

Candida auris has emerged globally as a multidrug-resistant health care-associated fungal pathogen. Recent reports highlight ongoing challenges due to organism misidentification, high rates of antifungal drug resistance, and significant patient mortality. The predilection for transmission within and between health care facilities possibly promoted by virulence factors that facilitate skin colonization and environmental persistence is unique among Candida species. This minireview details the global emergence of C. auris and discusses issues relevant to clinical microbiology laboratories, hospital infection control, and antimicrobial stewardship efforts.

Keywords: Candida auris; antifungal susceptibility; epidemiology; infection control.

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Figures

FIG 1
FIG 1
Dendrograms of Candida auris with other Candida species. Trimmed internal transcribed spacer 1/2 (A) and the long subunit (LSU) D1/D2 sequences (B) were aligned using MEGA7 software. The same software was used to draw the bootstrap (500 replicates) unweighted pair group method using average linkages (UPGMA) dendrograms constructed using a Kimura 2-parameter genetic distances model. Also of note, C. haemulonii (synonym C. haemulonis) is now considered a species complex composed of two species and one variety: C. haemulonii sensu stricto, C. duobushaemulonii, and C. haemulonis var. vulnera (45), and Clavispora lusitaniae is the current name for Candida lusitaniae. Accession numbers are shown to the right of the organism names.
See this image and copyright information in PMC

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