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. 2017 Jul;146(1):15-21.
doi: 10.4103/ijmr.IJMR_1485_16.

Shifting gears from embryonic to very small embryonic-like stem cells for regenerative medicine

Deepa Bhartiya  1
Affiliations

Shifting gears from embryonic to very small embryonic-like stem cells for regenerative medicine

Deepa Bhartiya. Indian J Med Res. 2017 Jul.
No abstract available

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Figures

Fig. 1
Fig. 1
Different types of pluripotent stem cells. MIAMI, Marrow-isolated adult multilineage inducible cells; MAPCs, Multipotent adult progenitor cells; MUSE, Multilineage-differentiating stress-enduring (Muse) cells; AFSCs, Amniotic fluid-derived stem cells.
Fig. 2
Fig. 2
Making human gametes from pluripotent stem cells. It is technically difficult to differentiate ES/iPS cells into primordial germ cells (PGCs) as it involved lot of epigenetic changes which may be difficult to replicate in vitro VSELs are developmentally linked to PGCs which are natural precursors to the gametes. Thus VSELs spontaneously differentiate into gametes.
See this image and copyright information in PMC

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References

    1. Bhartiya D, Shaikh A, Anand S, Patel H, Kapoor S, Sriraman K, et al. Endogenous, very small embryonic-like stem cells: Critical review, therapeutic potential and a look ahead. Hum Reprod Update. 2016;23:41–76. - PubMed
    1. Kumar N, Hinduja I, Nagvenkar P, Pillai L, Zaveri K, Mukadam L, et al. Derivation and characterization of two genetically unique human embryonic stem cell lines on in-house-derived human feeders. Stem Cells Dev. 2009;18:435–45. - PubMed
    1. Nagvenkar P, Pethe P, Pawani H, Telang J, Kumar N, Hinduja I, et al. Evaluating differentiation propensity of in-house derived human embryonic stem cell lines KIND-1 and KIND-2. In Vitro Cell Dev Biol Anim. 2011;47:406–19. - PubMed
    1. Pethe P, Nagvenkar P, Bhartiya D. Polycomb group protein expression during differentiation of human embryonic stem cells into pancreatic lineage in vitro . BMC Cell Biol. 2014;15:18. - PMC - PubMed
    1. Pawani H, Nagvenkar P, Pethe P, Bhartiya D. Differentiation of human ES cell line KIND-2 to yield tripotent cardiovascular progenitors. In Vitro Cell Dev Biol Anim. 2013;49:82–93. - PubMed

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