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Review
. 2017 Nov 23;18(12):2509.
doi: 10.3390/ijms18122509.

Coxiella burnetii Lipopolysaccharide: What Do We Know?

Prasad Abnave  1 , Xavier Muracciole  2 , Eric Ghigo  3
Affiliations
Review

Coxiella burnetii Lipopolysaccharide: What Do We Know?

Prasad Abnave et al. Int J Mol Sci. .

Abstract

A small gram-negative bacterium, Coxiella burnetii (C. burnetii), is responsible for a zoonosis called Q fever. C. burnetii is an intracellular bacterium that can survive inside microbicidal cells like monocytes and macrophages by hijacking several functions of the immune system. Among several virulence factors, the lipopolysaccharide (LPS) of C. burnetii is one of the major factors involved in this immune hijacking because of its atypical composition and structure. Thus, the aim of this mini-review is to summarize the repressive effects of C. burnetii LPS on the antibacterial immunity of cells.

Keywords: Coxiella burnetii; Q fever; lipopolysaccharide; phagosome; virenose.

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Conflict of interest statement

The authors declare no conflict of interest.

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