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Review
. 2018 Jun 1;56(2):75-84.
doi: 10.1515/rjim-2017-0045.

Biological therapies in psoriasis - revisited

Maria-Isabela Sârbu  1 , Simona-Roxana Georgescu  1   2 , Mircea Tampa  1   2 , Alexandra-Elena Sârbu  3 , Olga Simionescu  1   4
Affiliations
Free article
Review

Biological therapies in psoriasis - revisited

Maria-Isabela Sârbu et al. Rom J Intern Med. .
Free article

Abstract

Psoriasis is a chronic, immune mediated disorder affecting approximately 2% of the population. Even in our days, patients with psoriasis are confronted with stigmatization and social rejection. As a result, their quality of life is significantly impaired. Biological therapies have revolutionized the treatment of moderate to severe psoriasis. The aim of this paper is to look over the most important biological therapies available for the management of plaque-type psoriasis.

Keywords: IL-17; TNF-α; anti-IL-12/23; biological therapies; psoriasis.

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