Employing open/hidden administration in psychotherapy research: A randomized-controlled trial of expressive writing
- PMID: 29176768
- PMCID: PMC5703461
- DOI: 10.1371/journal.pone.0187400
Employing open/hidden administration in psychotherapy research: A randomized-controlled trial of expressive writing
Abstract
Psychotherapy has been shown to be effective, but efforts to prove specific effects by placebo-controlled trials have been practically and conceptually hampered. We propose that adopting open/hidden designs from placebo research would offer a possible way to establish specificity in psychotherapy. Therefore, we tested the effects of providing opposing treatment rationales in an online expressive writing intervention on affect in healthy subjects. Results indicate that it was possible to conduct the expressive writing intervention both covertly and openly, but that participants in the hidden administration condition did not fully benefit from the otherwise effective expressive writing intervention in the long-run. Effect sizes between open and hidden administration groups were comparable to pre-post effect sizes of the intervention. While this finding is important for the understanding of psychotherapy's effects per se, it also proves that alternative research approaches to establish specificity are feasible and informative in psychotherapy research.
Trial registration: German Clinical Trials Register DRKS00009428.
Conflict of interest statement
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References
-
- Kazdin AE. Mediators and mechanisms of change in psychotherapy research. Annu Rev Clin Psychol. 2007;3: 1–27. doi: 10.1146/annurev.clinpsy.3.022806.091432 - DOI - PubMed
-
- Beecher HK. The powerful placebo. J Am Med Assoc. 1955;159(17): 1602–1606. - PubMed
-
- Fergusson D, Glass KC, Waring D, Shapiro S. Turning a blind eye: the success of blinding reported in a random sample of randomised, placebo controlled trials. BMJ. 2004;328(7437): 432 doi: 10.1136/bmj.37952.631667.EE - DOI - PMC - PubMed
-
- Kirsch I. Placebo psychotherapy: Synonym or oxymoron? Journal of Clinical Psychology. 2005;61: 791–803. doi: 10.1002/jclp.20126 - DOI - PubMed
-
- Wampold B, Imel ZE. The great psychotherapy debate. 2nd ed. London and New York: Routledge; 2015.
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