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Review
. 2016 Dec;1(2):e05.
doi: 10.1097/IJ9.0000000000000005. Epub 2016 Nov 11.

Management of peritoneal surface malignancies in laparoscopic era: a concise review

Abhijit Shaligram  1
Affiliations
Review

Management of peritoneal surface malignancies in laparoscopic era: a concise review

Abhijit Shaligram. Int J Surg Oncol (N Y). 2016 Dec.

Abstract

Peritoneal carcinomatosis is seldom curable. Maximal cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy has been used in efforts to improve survival. There has been a recent explosion of interest in this modality of treatment with various centers employing its use throughout the world. This is a complex procedure associated with significant morbidity and mortality. This makes patient selection very critical and hence there has been immense interest in the evaluation of various prognostic indicators being evaluated. In addition, with the advent of minimally invasive surgery, laparoscopy is being increasingly utilized in different capacity. Newer indications for treatment and possible prevention of peritoneal carcinomatosis are being evaluated especially in colorectal cancer. The aim of this brief review is to synthesize and present the recent data available regarding the outcomes and evolving trends associated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

Keywords: Colorectal cancer; Cytoreductive surgery; Hyperthermic intraperitoneal chemotherapy (HIPEC); Laparoscopic; Peritoneal carcinomatosis.

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References

    1. Pilati P, Rossi CR, Mocellin S, et al. Multimodal treatment of peritoneal carcinomatosis and sarcomatosis. Eur J Surg Oncol 2001;27:125–134. - PubMed
    1. Chu DZ, Lang NP, Thompson C, et al. Peritoneal carcinomatosis in nongynecologic malignancy. A prospective study of prognostic factors. Cancer 1989;63:364–367. - PubMed
    1. Sugarbaker PH, Van Der Speeten K. Surgical technology and pharmacology of hyperthermic perioperative chemotherapy. J Gastrointest Oncol 2016;7:29–44. - PMC - PubMed
    1. Sugarbaker PH, Graves T, DeBruijn EA, et al. Early postoperative intraperitoneal chemotherapy as an adjuvant therapy to surgery for peritoneal carcinomatosis from gastrointestinal cancer: pharmacologic studies. Cancer Res 1990;50:5790–5794. - PubMed
    1. Verwaal VJ, Van Ruth S, Witkamp A, et al. Long-term survival of peritoneal carcinomatosis of colorectal origin. Ann Surg Oncol 2005;12:65–71. - PubMed

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