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. 2017 Dec;164(2):162-164.
doi: 10.1007/s10517-017-3948-y. Epub 2017 Nov 27.

Application of Preparations Containing Copper Nanoparticles for the Treatment of Experimental Septic Wounds

I V Babushkina  1 , E V Gladkova  2 , S V Belova  2 , I A Norkin  2
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Application of Preparations Containing Copper Nanoparticles for the Treatment of Experimental Septic Wounds

I V Babushkina et al. Bull Exp Biol Med. 2017 Dec.

Abstract

Regenerative activity of locally applied drugs based on copper nanoparticles was compared on white male rats with an experimental purulent wound infected with clinical polyantibiotic resistant strains of Staphylococcus aureus. The use of a suspension of copper nanoparticles and complex drugs based on chitosan and starch with copper nanoparticles led to a rapid reduction of the wound area and elimination of the wound-contaminating agent, which confirmed high antibacterial and regenerative activity of copper nanoparticles in the composition of the studied drugs.

Keywords: chitosan; copper; nanoparticles; purulent wound; starch.

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