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Review
. 2018 Feb;43(2):404-414.
doi: 10.1007/s00261-017-1394-y.

Genetics of pancreatic cancer and implications for therapy

Priya Bhosale  1 , Veronica Cox  2 , Silvana Faria  2 , Sanaz Javadi  2 , Chitra Viswanathan  2 , Eugene Koay  3 , Eric Tamm  2
Affiliations
Review

Genetics of pancreatic cancer and implications for therapy

Priya Bhosale et al. Abdom Radiol (NY). 2018 Feb.

Abstract

Pancreatic cancer is a highly lethal disease with a dismal 5-year prognosis. Knowledge of its genetics may help in identifying new methods for patient screening, and cancer treatment. In this review, we will describe the most common mutations responsible for the genesis of pancreatic cancer and their impact on screening, patterns of disease progression, and therapy.

Keywords: Genomics; Imaging; Mutations; Pancreatic cancer.

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