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Comment
. 2017 Nov;31(3):7.
doi: 10.15844/pedneurbriefs-31-3-1.

Neurotransmitters and Sodium Channelopathies; Possible Link?

Michael F Hammer  1 , Alejandra D C Encinas  2
Affiliations
Comment

Neurotransmitters and Sodium Channelopathies; Possible Link?

Michael F Hammer et al. Pediatr Neurol Briefs. 2017 Nov.

Abstract

Investigators from the University of British Columbia, Great Ormond Street Hospital for Children, and the National Hospital reported their findings on neurotransmitter deficiencies in two patients with mutations in voltage-gated sodium genes (SCN2A and SCN8A) discovered by whole exome sequencing.

Keywords: Channelopathy; Dopamine; Nav1.2; Nav1.6; SCN2A; SCN8A; Seizures; Serotonin; Therapy.

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References

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