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. 2018 Jan 1;75(1):98-100.
doi: 10.1001/jamapsychiatry.2017.3561.

Assessment of Symptom Network Density as a Prognostic Marker of Treatment Response in Adolescent Depression

Lizanne Schweren  1 , Claudia D van Borkulo  2 , Eiko Fried  2 , Ian M Goodyer  1
Affiliations

Assessment of Symptom Network Density as a Prognostic Marker of Treatment Response in Adolescent Depression

Lizanne Schweren et al. JAMA Psychiatry. .

Abstract

This cohort study uses the 33-item Mood and Feelings Questionnaire to examine whether symptom network density is associated with treatment response in adolescent depression.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Goodyer reported serving as a paid consultant for Lundbeck and licensing the Brief Psychosocial Intervention to Lundbeck for use in a clinical trial. No other disclosures were reported.

Figures

Figure 1.
Figure 1.. Network Structures of Depressive Symptoms in 233 Relatively Good and 232 Poor Responders to Treatment
Blue lines represent positive connections; red lines, negative connections; and thicker lines, stronger connections. For the symptom (node) abbreviations, agi indicates psychomotor agitation; con, concentration problems; dep, feeling sad/depressed; ene, loss of energy; gui, guilt/worthlessness; hyp, hypersomnia; ins, insomnia; int, loss of interest/pleasure; ret, psychomotor retardation; sui, suicidal ideation; and wap, weight or appetite change.
Figure 2.
Figure 2.. Differences in Total Mood and Feelings Questionnaire (MFQ) Mean Score, SD of the Mean Score, and Node Strength by Symptom Between Good and Poor Responders to Treatment
Red boxes outline statistically significant differences. Symptom (node) abbreviations are defined in the caption to Figure 1.
See this image and copyright information in PMC

References

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