A Fully-Closed and Automated Hollow Fiber Bioreactor for Clinical-Grade Manufacturing of Human Mesenchymal Stem/Stromal Cells

Amanda Mizukami¹, Mario Soares de Abreu Neto¹, Francisco Moreira², Ana Fernandes-Platzgummer^{2

3}, Yi-Feng Huang⁴, William Milligan^{4

5}, Joaquim M S Cabral^{2

3}, Cláudia L da Silva^{2

3}, Dimas T Covas¹, Kamilla Swiech^{6

7}

Affiliations

¹ Center for Cell-based Therapy, Regional Blood Center of Ribeirão Preto, University of São Paulo, Ribeirão Preto-SP, Brazil.
² Department of Bioengineering and IBB-Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.
³ The Discoveries Centre for Regenerative and Precision Medicine, Lisbon Campus, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.
⁴ R&D, AventaCell BioMedical Corp., Ltd., New Taipei City, Taiwan, Republic of China.
⁵ R&D, AventaCell BioMedical Corp., Ltd., Atlanta, GA, USA.
⁶ Center for Cell-based Therapy, Regional Blood Center of Ribeirão Preto, University of São Paulo, Ribeirão Preto-SP, Brazil. kamilla@fcfrp.usp.br.
⁷ Department of Pharmaceutical Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo., Av. do Café s/n, 14040-903, Ribeirão Preto, SP, Brazil. kamilla@fcfrp.usp.br.

PMID: 29188439
DOI: 10.1007/s12015-017-9787-4

A Fully-Closed and Automated Hollow Fiber Bioreactor for Clinical-Grade Manufacturing of Human Mesenchymal Stem/Stromal Cells

Amanda Mizukami et al. Stem Cell Rev Rep. 2018 Feb.

. 2018 Feb;14(1):141-143.

doi: 10.1007/s12015-017-9787-4.

Authors

Affiliations

¹ Center for Cell-based Therapy, Regional Blood Center of Ribeirão Preto, University of São Paulo, Ribeirão Preto-SP, Brazil.
² Department of Bioengineering and IBB-Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.
³ The Discoveries Centre for Regenerative and Precision Medicine, Lisbon Campus, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.
⁴ R&D, AventaCell BioMedical Corp., Ltd., New Taipei City, Taiwan, Republic of China.
⁵ R&D, AventaCell BioMedical Corp., Ltd., Atlanta, GA, USA.
⁶ Center for Cell-based Therapy, Regional Blood Center of Ribeirão Preto, University of São Paulo, Ribeirão Preto-SP, Brazil. kamilla@fcfrp.usp.br.
⁷ Department of Pharmaceutical Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo., Av. do Café s/n, 14040-903, Ribeirão Preto, SP, Brazil. kamilla@fcfrp.usp.br.

PMID: 29188439
DOI: 10.1007/s12015-017-9787-4

No abstract available

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A Fully-Closed and Automated Hollow Fiber Bioreactor for Clinical-Grade Manufacturing of Human Mesenchymal Stem/Stromal Cells

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A Fully-Closed and Automated Hollow Fiber Bioreactor for Clinical-Grade Manufacturing of Human Mesenchymal Stem/Stromal Cells

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