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Review
. 2018 Jun;7(1):1-17.
doi: 10.1007/s40123-017-0115-5. Epub 2017 Nov 30.

A Review of the Landscape of Targeted Immunomodulatory Therapies for Non-Infectious Uveitis

Affiliations
Review

A Review of the Landscape of Targeted Immunomodulatory Therapies for Non-Infectious Uveitis

Srilakshmi M Sharma et al. Ophthalmol Ther. 2018 Jun.

Abstract

Systemic immunomodulatory therapies are the principal means of managing non-infectious uveitis. This review aims to explore the current landscape of systemic uveitis treatments, including biologic therapies and the advent of biosimilar therapies.

Keywords: Biologics; Biosimilars; Interferon; Interleukins; Non-infectious uveitis; TNFα inhibitors.

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References

    1. Al-Rayes H, Al-Swailem R, Al-Balawi M, Al-Dohayan N, Al-Zaidi S, Tariq M. Safety and efficacy of infliximab therapy in active Behcet’s uveitis: an open-label trial. Rheumatol Int. 2008;29(1):53–57. doi: 10.1007/s00296-008-0606-8. - DOI - PubMed
    1. Angeles-Han S, Flynn T, Lehman T. Abatacept for refractory juvenile idiopathic arthritis-associated uveitis- a case report. J Rheumatol. 2008;35(9):1897–1898. - PubMed
    1. Artornsombudh P, Gevorgyan O, Payal A, Siddique SS, Foster CS. Infliximab treatment of patients with birdshot retinochoroidopathy. Ophthalmology. 2013;120(3):588–592. doi: 10.1016/j.ophtha.2012.05.048. - DOI - PubMed
    1. Baarsma GS. The epidemiology and genetics of endogenous uveitis: a review. Curr Eye Res. 1992;11(Suppl):1–9. doi: 10.3109/02713689208999505. - DOI - PubMed
    1. Baert F, Noman M, Vermeire S, Van Assche G, D’Haens G, Carbonez A, Rutgeerts P. Influence of immunogenicity on the long-term efficacy of infliximab in Crohn’s disease. N Engl J Med. 2003;348(7):601–608. doi: 10.1056/NEJMoa020888. - DOI - PubMed

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