Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Apr 1;34(7):1235-1237.
doi: 10.1093/bioinformatics/btx754.

bioBakery: a meta'omic analysis environment

Affiliations

bioBakery: a meta'omic analysis environment

Lauren J McIver et al. Bioinformatics. .

Abstract

Summary: bioBakery is a meta'omic analysis environment and collection of individual software tools with the capacity to process raw shotgun sequencing data into actionable microbial community feature profiles, summary reports, and publication-ready figures. It includes a collection of pre-configured analysis modules also joined into workflows for reproducibility.

Availability and implementation: bioBakery (http://huttenhower.sph.harvard.edu/biobakery) is publicly available for local installation as individual modules and as a virtual machine image. Each individual module has been developed to perform a particular task (e.g. quantitative taxonomic profiling or statistical analysis), and they are provided with source code, tutorials, demonstration data, and validation results; the bioBakery virtual image includes the entire suite of modules and their dependencies pre-installed. Images are available for both Amazon EC2 and Google Compute Engine. All software is open source under the MIT license. bioBakery is actively maintained with a support group at biobakery-users@googlegroups.com and new tools being added upon their release.

Contact: chuttenh@hsph.harvard.edu.

Supplementary information: Supplementary data are available at Bioinformatics online.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
The default metagenome workflow incorporates several individual tools that together process raw sequences into a set of data products, reports and visualizations

References

    1. Abubucker S. et al. (2012) Metabolic reconstruction for metagenomic data and its application to the human microbiome. PLoS Comput. Biol., 8, e1002358. - PMC - PubMed
    1. Daniela B. et al. (2015) A reproducible approach to high-throughput biological data acquisition and integration. PeerJ., 3, e791. - PMC - PubMed
    1. Duy T.T. et al. (2017) Microbial strain-level population structure and genetic diversity from metagenomes. Genome Res., 27, 626–638. - PMC - PubMed
    1. Kaminski J. et al. (2015) High-specificity targeted functional profiling in microbial communities with ShortBRED. PLoS Comput. Biol., 11, e1004557. - PMC - PubMed
    1. Langille M.G.I. et al. (2013) Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences. Nat. Biotechnol., 8, 1–10. - PMC - PubMed

Publication types