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Review
. 2017 Dec;17(6):558-561.
doi: 10.7861/clinmedicine.17-6-558.

A clinical approach to developmental delay and intellectual disability

Pradeep Vasudevan  1 , Mohnish Suri  2
Affiliations
Review

A clinical approach to developmental delay and intellectual disability

Pradeep Vasudevan et al. Clin Med (Lond). 2017 Dec.

Abstract

Global developmental delay and intellectual disability are phenotypically and genetically heterogeneous and a specific diagnosis is not reached in many cases. This paper outlines a systematic approach to global developmental delay and intellectual disability.

Keywords: Chromosomal micro-array; WES; WGS; clinical exome; global developmental delay; intellectual diasbility; learning disability.

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Figures

Fig 1.
Fig 1.
A suggested diagnostic pathway for global developmental delay/intellectual disability. CES = clinical exome sequencing; GDD = global developmental delay; ID = intellectual disability; WES = whole exome sequencing; WGS = whole genome sequencing
See this image and copyright information in PMC

Comment in

  • Not only what investigations? When, why, at what cost, whose choice?
    Cooper B. Cooper B. Clin Med (Lond). 2018 Mar;18(2):191-192. doi: 10.7861/clinmedicine.18-2-191a. Clin Med (Lond). 2018. PMID: 29626038 Free PMC article. No abstract available.
  • Response.
    Vasudevan PC, Suri M. Vasudevan PC, et al. Clin Med (Lond). 2018 Mar;18(2):192. doi: 10.7861/clinmedicine.18-2-192. Clin Med (Lond). 2018. PMID: 29626039 Free PMC article. No abstract available.

References

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MeSH terms