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. 2018:1710:191-201.
doi: 10.1007/978-1-4939-7498-6_15.

Immunohistological Techniques

Evangelina Capobianco  1 , Nora Martinez  2
Affiliations

Immunohistological Techniques

Evangelina Capobianco et al. Methods Mol Biol. 2018.

Abstract

Preeclampsia is associated with histological alterations in the placenta. These alterations can be described by means of histological techniques. More specifically, immunohistochemistry could be used to detect proteins, and these in turn may be used to identify a specific cell type, to differentiate it from other cell types and to detect the expression of some markers deregulated in preeclampsia.This chapter focuses on the detection of specific cellular and molecular markers that evidence the alterations in the human placenta in preeclampsia.

Keywords: Cytotrophoblast; Immunohistochemistry; Placental molecular markers; Preeclampsia; Syncytiotrophoblast.

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