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Review
. 2017 Dec:120:34-42.
doi: 10.1016/j.critrevonc.2017.10.005. Epub 2017 Oct 16.

Fertility management for malignant ovarian germ cell tumors patients

Chiara Di Tucci  1 , Assunta Casorelli  2 , Elisa Morrocchi  2 , Innocenza Palaia  2 , Ludovico Muzii  2 , Pierluigi Benedetti Panici  2
Affiliations
Review

Fertility management for malignant ovarian germ cell tumors patients

Chiara Di Tucci et al. Crit Rev Oncol Hematol. 2017 Dec.

Abstract

Malignant Germ Cell Tumors have primarily affecting adolescents and young adults. In advanced disease, greater than 70% of patients can be cured with standard chemotherapy regimens and fertility-sparing surgery appears to be safe with excellent survival after long-term follow-up. Due to their rarity, follow up and fertility management is largely based on trials of epithelial ovarian cancer or on few small studies. We report a review of the literature studies about the assessment, the monitoring and the treatment of fertility for Malignant Germ Cell Tumors as pratical guidelines for management of fertility in these patients.

Keywords: Fertility; Germ cell cancer; Management; Ovarian cancer; Ovarian germ cell tumor; Treatment.

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