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Comment
. 2018 Jan;24(1):1-3.
doi: 10.1016/j.molmed.2017.11.007. Epub 2017 Dec 5.

Pregnancy Around the Clock

Anke Diemert  1 , Petra Clara Arck  2
Affiliations
Comment

Pregnancy Around the Clock

Anke Diemert et al. Trends Mol Med. 2018 Jan.

Abstract

A recent study introduced the existence of an 'immune clock' in pregnancy; during the course of gestation, peripheral blood cells from pregnant women were analyzed by mass cytometry using a single-cell signaling-based elastic net algorithm. The insights will undoubtedly promote the testing of such a clock - possibly in synergy with other pacemakers - to potentially predict pregnancy complications.

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  • An immune clock of human pregnancy.
    Aghaeepour N, Ganio EA, Mcilwain D, Tsai AS, Tingle M, Van Gassen S, Gaudilliere DK, Baca Q, McNeil L, Okada R, Ghaemi MS, Furman D, Wong RJ, Winn VD, Druzin ML, El-Sayed YY, Quaintance C, Gibbs R, Darmstadt GL, Shaw GM, Stevenson DK, Tibshirani R, Nolan GP, Lewis DB, Angst MS, Gaudilliere B. Aghaeepour N, et al. Sci Immunol. 2017 Sep 1;2(15):eaan2946. doi: 10.1126/sciimmunol.aan2946. Sci Immunol. 2017. PMID: 28864494 Free PMC article.

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