Chromosome 15 Duplication and Attention-Deficit Hyperactivity Disorder
- PMID: 29204034
- PMCID: PMC5709897
- DOI: 10.4103/jnrp.jnrp_316_17
Chromosome 15 Duplication and Attention-Deficit Hyperactivity Disorder
Abstract
Chromosome 15 duplication has been associated with a number of psychiatric illnesses including psychosis and autism. However, literature on association with attention-deficit hyperactivity disorder (ADHD) is scant. This case report describes a patient with chromosome 15 duplication diagnosed with ADHD in our neurodevelopmental clinic. The possible biological underpinnings are discussed along with possible challenges in diagnosis and management. The need for better understanding ADHD as a behavioral phenotype in such cases along with need for tailored management strategies is emphasized.
Keywords: Attention-deficit hyperactivity disorder; chromosome 15 duplication; genetics.
Conflict of interest statement
There are no conflicts of interest.
References
-
- Bolton PF, Dennis NR, Browne CE, Thomas NS, Veltman MW, Thompson RJ, et al. The phenotypic manifestations of interstitial duplications of proximal 15q with special reference to the autistic spectrum disorders. Am J Med Genet. 2001;105:675–85. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources