Clinicopathological Study of Pediatric Posterior Fossa Tumors
- PMID: 29204199
- PMCID: PMC5696661
- DOI: 10.4103/jpn.JPN_113_16
Clinicopathological Study of Pediatric Posterior Fossa Tumors
Abstract
Context: Brain tumor is one of the most devastating forms of human illness, especially when occurring in the posterior fossa and involving the brainstem. Tumors in the posterior fossa are considered some of the most critical brain lesions. This is primarily due to the limited space within the posterior fossa, as well as the potential involvement of the vital brainstem nuclei.
Aims: The aim of this study is to analyze the incidence, clinical features, surgical outcome, complications, and prognosis in a series of 37 pediatric patients with posterior fossa tumors who underwent surgery between September 2012 and January 2015 from the Department of Neurosurgery, King George Hospital, Visakhapatnam (both prospective and retrospective study).
Materials and methods: A series of 37 cases were treated by the Department of Neurosurgery, King George Hospital, between August 2012 and January 2015.
Results: Posterior fossa tumors are predominantly seen in children with a peak incidence in the first decade. The most common presenting symptoms are raised intracranial pressure with headache and vomiting. Majority of the tumors are medulloblastomas, ependymomas, and cerebellar astrocytomas. The most common location is the cerebellar vermis, followed by the cerebellar hemispheres, followed by the forth ventricle and then the brainstem.
Keywords: Hydrocephalus; pediatric tumors; posterior fossa.
Conflict of interest statement
There are no conflicts of interest.
References
-
- Cushing H. Experience with the cerebellar medulloblastoma: Critical review. Acta Pathol Microbiol Immunol Scand. 1930;7:1–86.
-
- Allen JC. Childhood brain tumors: Current status of clinical trials in newly diagnosed and recurrent disease. Pediatr Clin North Am. 1985;32:633–51. - PubMed
-
- Laurent JP, Cheek WR. Brain tumours in children. J Pediatr Neurosci. 1985;1:15–32.
-
- O’Brien DF, Caird J, Kennedy M, Roberts GA, Marks JC, Allcutt DA. Posterior fossa tumours in childhood: Evaluation of presenting clinical features. Ir Med J. 2001;94:52–3. - PubMed
-
- Lannering B, Marky I, Nordborg C. Brain tumors in childhood and adolescence in west Sweden 1970-1984. Epidemiology and survival. Cancer. 1990;66:604–9. - PubMed
LinkOut - more resources
Full Text Sources
Other Literature Sources