Modeling Drug Disposition and Drug-Drug Interactions Through Hypothesis-Driven Physiologically Based Pharmacokinetics: a Reversal Translation Perspective

Guo-Fu Li^{1

2}, Qing-Shan Zheng³

Affiliations

¹ Center for Drug Clinical Research, Shanghai University of Chinese Medicine, No. 1200 Cailun Rd, Shanghai, 201203, China. guofu.g.li@gmail.com.
² Department of Pharmaceutics, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL, 32610, USA. guofu.g.li@gmail.com.
³ Center for Drug Clinical Research, Shanghai University of Chinese Medicine, No. 1200 Cailun Rd, Shanghai, 201203, China. qingshan.q.zheng@gmail.com.

PMID: 29204788
DOI: 10.1007/s13318-017-0452-8

Comment

Modeling Drug Disposition and Drug-Drug Interactions Through Hypothesis-Driven Physiologically Based Pharmacokinetics: a Reversal Translation Perspective

Guo-Fu Li et al. Eur J Drug Metab Pharmacokinet. 2018 Jun.

. 2018 Jun;43(3):369-371.

doi: 10.1007/s13318-017-0452-8.

Authors

Guo-Fu Li^{1

2}, Qing-Shan Zheng³

Affiliations

¹ Center for Drug Clinical Research, Shanghai University of Chinese Medicine, No. 1200 Cailun Rd, Shanghai, 201203, China. guofu.g.li@gmail.com.
² Department of Pharmaceutics, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL, 32610, USA. guofu.g.li@gmail.com.
³ Center for Drug Clinical Research, Shanghai University of Chinese Medicine, No. 1200 Cailun Rd, Shanghai, 201203, China. qingshan.q.zheng@gmail.com.

PMID: 29204788
DOI: 10.1007/s13318-017-0452-8

No abstract available

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Physiologically Based Pharmacokinetic Modelling of Cytochrome P450 2C9-Related Tolbutamide Drug Interactions with Sulfaphenazole and Tasisulam.
Perkins EJ, Posada M, Kellie Turner P, Chappell J, Ng WT, Twelves C. Perkins EJ, et al. Eur J Drug Metab Pharmacokinet. 2018 Jun;43(3):355-367. doi: 10.1007/s13318-017-0447-5. Eur J Drug Metab Pharmacokinet. 2018. PMID: 29119333 Free PMC article.

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References

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Modeling Drug Disposition and Drug-Drug Interactions Through Hypothesis-Driven Physiologically Based Pharmacokinetics: a Reversal Translation Perspective

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Modeling Drug Disposition and Drug-Drug Interactions Through Hypothesis-Driven Physiologically Based Pharmacokinetics: a Reversal Translation Perspective

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