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Review
. 2017:1041:55-79.
doi: 10.1007/978-3-319-69194-7_5.

Spinal Cord Stem Cells In Their Microenvironment: The Ependyma as a Stem Cell Niche

Nicolás Marichal  1   2 , Cecilia Reali  1 , Omar Trujillo-Cenóz  1 , Raúl E Russo  3
Affiliations
Review

Spinal Cord Stem Cells In Their Microenvironment: The Ependyma as a Stem Cell Niche

Nicolás Marichal et al. Adv Exp Med Biol. 2017.

Abstract

The ependyma of the spinal cord is currently proposed as a latent neural stem cell niche. This chapter discusses recent knowledge on the developmental origin and nature of the heterogeneous population of cells that compose this stem cell microenviroment, their diverse physiological properties and regulation. The chapter also reviews relevant data on the ependymal cells as a source of plasticity for spinal cord repair.

Keywords: Central canal; Neural stem cells; Plasticity; Progenitor cells; Radial glia; Regeneration; Spinal cord.

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