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Review
. 2018 Jan;21(1):64-69.
doi: 10.1111/1756-185X.13220. Epub 2017 Dec 5.

Role of intravenous immunoglobulin in the treatment of Kawasaki disease

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Review

Role of intravenous immunoglobulin in the treatment of Kawasaki disease

Mindy S Lo et al. Int J Rheum Dis. 2018 Jan.

Abstract

Intravenous immunoglobulin (IVIg) is a purified plasma product that is used for many immune-deficient conditions and autoimmune conditions. Use of IVIg for treatment for Kawasaki disease (KD) is critical for control of inflammation. The American Heart Association (AHA) recommends a single infusion of 2 g/kg preferably given during the first 10 days of illness. In this review, we have discussed the possible mechanisms of action of IVIg in KD and its clinical usage in this condition.

Keywords: Kawasaki disease; intravenous immunoglobulin.

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