Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Jan;11(1):160-162.
doi: 10.1111/1751-7915.12869. Epub 2017 Dec 4.

Facile methods for heterologous production of bacterial microcompartments in diverse host species

Todd O Yeates  1   2 , Thomas A Bobik  3
Affiliations
Review

Facile methods for heterologous production of bacterial microcompartments in diverse host species

Todd O Yeates et al. Microb Biotechnol. 2018 Jan.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
An idealized structural and metabolic model for the propanediol utilization (Pdu) bacterial microcompartment (MCP). A few thousand protein subunits, most belonging to the family of BMC shell proteins, encapsulate a series of enzymes for metabolizing 1,2‐propanediol (1,2‐PD) without allowing escape of the toxic aldehyde intermediate. Substrates and product pass selectively through pores in the shell proteins.
See this image and copyright information in PMC

References

    1. Abdul‐Rahman, F. , Petit, E. , and Blanchard, J.L. (2013) The distribution of polyhedral bacterial microcompartments suggests frequent horizontal transfer and operon reassembly. J Phylogen Evol Biol 1: 118 https://doi.org/10.4172/2329-9002.1000118. - DOI
    1. Axen, S.D. , Erbilgin, O. , and Kerfeld, C.A. (2014) A taxonomy of bacterial microcompartment loci constructed by a novel scoring method. PLoS Comput Biol 10: e1003898. - PMC - PubMed
    1. Bale, J.B. , Gonen, S. , Liu, Y. , Sheffler, W. , Ellis, D. , Thomas, C. , et al (2016) Accurate design of megadalton‐scale two‐component icosahedral protein complexes. Science 353: 389–394. - PMC - PubMed
    1. Bobik, T.A. , Lehman, B.P. , and Yeates, T.O. (2015) Bacterial microcompartments: widespread prokaryotic organelles for isolation and optimization of metabolic pathways. Mol Microbiol 98: 193–207. - PMC - PubMed
    1. Bonacci, W. , Teng, P.K. , Afonso, B. , Niederholtmeyer, H. , Grob, P. , Silver, P.A. , and Savage, D.F. (2012) Modularity of a carbon‐fixing protein organelle. Proc Natl Acad Sci USA 109: 478–483. - PMC - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources