Conflict of Interest: • Dr Bischof reports grants from Freiwillige Akademische Gesellschaft, Basel, Switzerland and Gottfried and Julia Bangerter–Rhyner Foundation during the conduct of the study; Dr Bischof's institution (University Hospital Basel) has received the following grants that were exclusively used for research support: speaker fees from Biogen and travel support from Actelion, outside the submitted work.• Dr Cordano has nothing to disclose.• Dr Henry reports personal fees from Roche and Stem Cells Inc., outside the submitted work.• SL Hauser serves on the Scientific Advisory Boards for Annexon Biosciences, Symbiotix, Bionure, and Molecular Stethoscope. He is on the Board of Trustees for Neurona Therapeutics. Dr Hauser has also received travel reimbursement and writing assistance from F. Hoffmann-La Roche Ltd. for CD20-related meetings and presentations.