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Case Reports
. 2017 Sep;11(9):OD16-OD17.
doi: 10.7860/JCDR/2017/30445.10662. Epub 2017 Sep 1.

Syndrome of Inappropriate Secretion of Antidiuretic Hormone Preceding Guillain-Barré Syndrome

Joe James  1 , James Jose  2
Affiliations
Case Reports

Syndrome of Inappropriate Secretion of Antidiuretic Hormone Preceding Guillain-Barré Syndrome

Joe James et al. J Clin Diagn Res. 2017 Sep.

Abstract

Guillain-Barré Syndrome (GBS) is an inflammatory polyradiculoneuropathy which is known to produce syndrome of inappropriate Secretion of Antidiuretic Hormone (SIADH). However, the hyponatremia is usually seen after the onset of weakness. Here, we report a case of SIADH that presented with hyponatremic seizures which preceded the onset of GBS by ten days.

Keywords: Hyponatremia; Polyneuropathies; Seizures.

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References

    1. Saifudheen K, Jose J, Gafoor VA, Musthafa M. Guillain-barre syndrome and SIADH. Neurology. 2011;76(8):701–04. - PubMed
    1. Usalan C, Erdem Y, Altun B. Severe hyponatremia due to SIADH provoked by acute intermittent porphyria. Clin Nephrol. 1996;45(6):418. - PubMed
    1. Hoffmann O, Reuter U, Schielke E, Weber JR. SIADH as the first symptom of guillain-barre syndrome. Neurology. 1999;53(6):1365. - PubMed
    1. Ramanathan S, McMeniman J, Cabela R, Holmes-Walker DJ, Fung VSC. SIADH and dysautonomia as the initial presentation of guillain-barre syndrome. J Neurol Neurosurg Psychiatry. 2011;83(3):344–45. - PubMed
    1. Posner JB. Hyponatremia in acute polyneuropathy. Arch Neurol. 1967;17(5):530. - PubMed

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