Review

. 2017 Dec 5;21(1):296.

doi: 10.1186/s13054-017-1887-7.

Recovery after critical illness: putting the puzzle together-a consensus of 29

Elie Azoulay¹, Jean-Louis Vincent², Derek C Angus³, Yaseen M Arabi⁴, Laurent Brochard⁵, Stephen J Brett⁶, Giuseppe Citerio⁷, Deborah J Cook⁸, Jared Randall Curtis⁹, Claudia C Dos Santos¹⁰, E Wesley Ely¹¹, Jesse Hall¹², Scott D Halpern¹³, Nicholas Hart¹⁴, Ramona O Hopkins^{15

16}, Theodore J Iwashyna¹⁷, Samir Jaber¹⁸, Nicola Latronico¹⁹, Sangeeta Mehta²⁰, Dale M Needham²¹, Judith Nelson²², Kathleen Puntillo²³, Michael Quintel²⁴, Kathy Rowan²⁵, Gordon Rubenfeld²⁶, Greet Van den Berghe²⁷, Johannes Van der Hoeven²⁶, Hannah Wunsch²⁸, Margaret Herridge²⁹

Affiliations

¹ Medical Intensive Care Unit, Hôpital Saint-Louis, ECSTRA team, Biostatistics and clinical epidemiology, UMR 1153 (Center of Epidemiology and Biostatistics Sorbonne Paris Cité, CRESS), INSERM, Paris Diderot Sorbonne University, Paris, France. elie.azoulay@sls.aphp.fr.
² Erasme Hospital, Université libre de Bruxelles, Brussels, Belgium.
³ The University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
⁴ King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
⁵ St. Michael's Hospital, Toronto, ON, Canada.
⁶ Department of Surgery and Cancer Imperial College, London, UK.
⁷ Università Milano Bicocca, Milano, Italy.
⁸ McMaster University Medical Center, Hamilton, ON, Canada.
⁹ Cambia Palliative Care Center of Excellence, Seattle, WA, USA.
¹⁰ Toronto General Research Institute, University of Toronto, Toronto, ON, Canada.
¹¹ Vanderbilt University School of Medicine, and TN Valley Veteran's Affairs Geriatric Research Education Clinical Center (GRECC), Nashville, TN, USA.
¹² The University of Chicago, Chicago, IL, USA.
¹³ Perelman School of Medicine, Philadelphia, PA, USA.
¹⁴ St Thomas Hospital, London, UK.
¹⁵ Intermountain Medical Center, Murray, UT, USA.
¹⁶ Psychology Department and Neuroscience Center, Brigham Young University, Provo, UT, USA.
¹⁷ University of Michigan Health System, and Ann Arbor Veterans Affairs Healthcare System, Ann Arbor, MI, USA.
¹⁸ Saint-Eloi Hospital, Montpellier, France.
¹⁹ University of Brescia at Spedali Civili, Brescia, Italy.
²⁰ Mount Sinai Hospital, Toronto, ON, Canada.
²¹ Johns Hopkins University School of Medicine, Baltimore, MD, USA.
²² Memorial Sloan Kettering Cancer Center, and Weill Cornell Medical College New York, New York, NY, USA.
²³ University of California, San Francisco, CA, USA.
²⁴ University Hospital Göttingen, Göttingen, Germany.
²⁵ Intensive Care National Audit & Research Centre, London, UK.
²⁶ Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
²⁷ University Hospital Leuven, Leuven, Belgium.
²⁸ Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.
²⁹ Toronto General Research Institute, University of Toronto, UHN - University Health Network, Toronto, ON, Canada.

PMID: 29208005
PMCID: PMC5718148
DOI: 10.1186/s13054-017-1887-7

Review

Recovery after critical illness: putting the puzzle together-a consensus of 29

Elie Azoulay et al. Crit Care. 2017.

. 2017 Dec 5;21(1):296.

doi: 10.1186/s13054-017-1887-7.

Authors

Affiliations

¹ Medical Intensive Care Unit, Hôpital Saint-Louis, ECSTRA team, Biostatistics and clinical epidemiology, UMR 1153 (Center of Epidemiology and Biostatistics Sorbonne Paris Cité, CRESS), INSERM, Paris Diderot Sorbonne University, Paris, France. elie.azoulay@sls.aphp.fr.
² Erasme Hospital, Université libre de Bruxelles, Brussels, Belgium.
³ The University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
⁴ King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
⁵ St. Michael's Hospital, Toronto, ON, Canada.
⁶ Department of Surgery and Cancer Imperial College, London, UK.
⁷ Università Milano Bicocca, Milano, Italy.
⁸ McMaster University Medical Center, Hamilton, ON, Canada.
⁹ Cambia Palliative Care Center of Excellence, Seattle, WA, USA.
¹⁰ Toronto General Research Institute, University of Toronto, Toronto, ON, Canada.
¹¹ Vanderbilt University School of Medicine, and TN Valley Veteran's Affairs Geriatric Research Education Clinical Center (GRECC), Nashville, TN, USA.
¹² The University of Chicago, Chicago, IL, USA.
¹³ Perelman School of Medicine, Philadelphia, PA, USA.
¹⁴ St Thomas Hospital, London, UK.
¹⁵ Intermountain Medical Center, Murray, UT, USA.
¹⁶ Psychology Department and Neuroscience Center, Brigham Young University, Provo, UT, USA.
¹⁷ University of Michigan Health System, and Ann Arbor Veterans Affairs Healthcare System, Ann Arbor, MI, USA.
¹⁸ Saint-Eloi Hospital, Montpellier, France.
¹⁹ University of Brescia at Spedali Civili, Brescia, Italy.
²⁰ Mount Sinai Hospital, Toronto, ON, Canada.
²¹ Johns Hopkins University School of Medicine, Baltimore, MD, USA.
²² Memorial Sloan Kettering Cancer Center, and Weill Cornell Medical College New York, New York, NY, USA.
²³ University of California, San Francisco, CA, USA.
²⁴ University Hospital Göttingen, Göttingen, Germany.
²⁵ Intensive Care National Audit & Research Centre, London, UK.
²⁶ Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
²⁷ University Hospital Leuven, Leuven, Belgium.
²⁸ Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.
²⁹ Toronto General Research Institute, University of Toronto, UHN - University Health Network, Toronto, ON, Canada.

PMID: 29208005
PMCID: PMC5718148
DOI: 10.1186/s13054-017-1887-7

Abstract

In this review, we seek to highlight how critical illness and critical care affect longer-term outcomes, to underline the contribution of ICU delirium to cognitive dysfunction several months after ICU discharge, to give new insights into ICU acquired weakness, to emphasize the importance of value-based healthcare, and to delineate the elements of family-centered care. This consensus of 29 also provides a perspective and a research agenda about post-ICU recovery.

Keywords: Cognitive dysfunction; Delirium; Depression; Intensive care; Mechanical ventilation; Muscular disorder; Sedation; Traumatic stress; Weakness.

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Conflict of interest statement

Ethics approval and consent to participate

Not applicable.

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

References

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1. Pandharipande PP, Girard TD, Jackson JC, Morandi A, Thompson JL, Pun BT, Brummel NE, Hughes CG, Vasilevskis EE, Shintani AK, Moons KG, Geevarghese SK, Canonico A, Hopkins RO, Bernard GR, Dittus RS, Ely EW, BRAIN-ICU Study Investigators Long-term cognitive impairment after critical illness. N Engl J Med. 2013;369(14):1306–16. doi: 10.1056/NEJMoa1301372. - DOI - PMC - PubMed

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Recovery after critical illness: putting the puzzle together-a consensus of 29

Affiliations

Recovery after critical illness: putting the puzzle together-a consensus of 29

Authors

Affiliations

Abstract

Conflict of interest statement

Ethics approval and consent to participate

Consent for publication

Competing interests

Publisher’s Note

References

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical