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Editorial
. 2018 Jan 6;13(1):6-8.
doi: 10.2215/CJN.12021017. Epub 2017 Dec 5.

Lowering Expectations with Niacin Treatment for CKD-MBD

Tilman B Drüeke  1 , Ziad A Massy  1   2
Affiliations
Editorial

Lowering Expectations with Niacin Treatment for CKD-MBD

Tilman B Drüeke et al. Clin J Am Soc Nephrol. .
No abstract available

Keywords: Bone Diseases, Metabolic; Chronic Kidney Disease-Mineral and Bone Disorder; Probability; Renal Insufficiency, Chronic; chronic kidney disease; hyperphosphatemia; mineral metabolism; niacin; nicotinic acid; phosphate binders; phosphate transport inhibitors.

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Figures

Figure 1.
Figure 1.
Schematic view of the action of oral inhibitors of active intestinal phosphate absorption compared with the chelation of phosphate in the gut lumen by oral phosphate binders. Modified from reference , with permission.
See this image and copyright information in PMC

Comment on

References

    1. Ginsberg C, Ix JH: Nicotinamide and phosphate homeostasis in chronic kidney disease. Curr Opin Nephrol Hypertens 25: 285–291, 2016 - PMC - PubMed
    1. Lenglet A, Liabeuf S, Guffroy P, Fournier A, Brazier M, Massy ZA: Use of nicotinamide to treat hyperphosphatemia in dialysis patients. Drugs R D 13: 165–173, 2013 - PMC - PubMed
    1. Kamanna VS, Kashyap ML: Mechanism of action of niacin. Am J Cardiol 101: 20B–26B, 2008 - PubMed
    1. Bodor ET, Offermanns S: Nicotinic acid: An old drug with a promising future. Br J Pharmacol 153[Suppl 1]: S68–S75, 2008 - PMC - PubMed
    1. Block GA, Rosenbaum DP, Leonsson-Zachrisson M, Åstrand M, Johansson S, Knutsson M, Langkilde AM, Chertow GM: Effect of tenapanor on serum phosphate in patients receiving hemodialysis. J Am Soc Nephrol 28: 1933–1942, 2017 - PMC - PubMed