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Case Reports
. 2017 Jun;9(2):115-119.

Primary umbilical endometriosis: a case report

Affiliations
Case Reports

Primary umbilical endometriosis: a case report

Dpa Van den Nouland et al. Facts Views Vis Obgyn. 2017 Jun.

Abstract

Primary umbilical endometriosis is a rare phenomenon accounting for 0,4-1,0% of extragenital endometriosis. Despite the fact that it mostly presents as a typical cyclic umbilical discharge coincidental with a palpable mass, the diagnosis is often delayed due to its low prevalence, as was seen in the presented case. The exact pathogenesis is still unclear. The golden standard for diagnosis is histopathological examination, but diagnostic tools like ultrasound, MRI or CT scan can be helpful. The differential diagnosis includes a wide range of disorders. Surgical management is the preferred treatment.

Keywords: Cutaneous endometriosis; diagnosis; extragenital endometriosis; primary umbilical endometriosis; treatment.

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Figures

Figure 1
Figure 1
— A superficial hyperpigmented dark reddish to violaceous nodule, located in the umbilicus of approximately 1 cm.
Figure 2
Figure 2
— The abdominal ultrasound, showing a superficial nodule of 1.15 to 1.07cm in the umbilicus.
Figure 3
Figure 3
— Fibro-adipose connective tissue with prevalence of multiple endometrial glandular tubes and surrounding endometrial stroma..
Figure 4
Figure 4
— Postoperative umbilical scar

References

    1. Bischoff FZ, Simpson JL. Heritability and molecular genetic studies of endometriosis. Hum Reprod Update. 2000;6:37–44. - PubMed
    1. Boesgaard-Kjer D, Boesgaard-Kjer D, Kjer JJ. Primary umbilical endometriosis (PUE). Eur J Obstet Gynecol Reprod Biol. 2017;209:44–45. - PubMed
    1. Bulun SE. Endometriosis. N Engl J Med. 2009;360:268–279. - PubMed
    1. Cakmak H, Guzeloglu-Kayisli O, Kayisli UA, et al. Immune- endocrine interactions in endometriosis. Front Biosci (Elite Ed) 2009;1:429–443. - PubMed
    1. Calagna G, Perino A, Chianetta D, et al. Primary umbilical endometrioma: Analyzing the pathogenesis of endometriosis from an unusual localization. Taiwan J Obstet Gynecol. 2015;54:306–312. - PubMed

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