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. 2017 Dec;38(12):1213-1218.
doi: 10.15537/smj.2017.12.21463.

Inflammatory parameters in sexually abused children

Affiliations

Inflammatory parameters in sexually abused children

Serbülent Kılıç et al. Saudi Med J. 2017 Dec.

Abstract

To investigate whether serum levels of cortisol, interleukin-6 and interleukin-10 differed between children with or without a sexual trauma. Methods: This descriptive study was conducted in the Department of Child Protective Service (CPS), Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey, between May 2016 and July 2016. Three different markers (cortisol, interleukin-6 and interleukin-10) were used to perform this experiment. We included 17 children age less than 18 years old and sexually abused, and 10 children who were not abused as a control group. The levels of cortisol, interleukin-6, and interleukin-10 were measured in blood samples using enzyme-linked immunosorbent assay method. The results of the experiment were statistically analyzed. Results: The findings indicate that serum levels of interleukin-6 were higher in the sexually abused children compared with the control group (p=0.002). There were no significant differences in the serum levels of cortisol (p=0.604) and interleukin-10 (p=0.835) between the sexually abused children and the control group. Conclusion: No significant differences were seen between the patients with or without sexual assault in terms of cortisol and IL-10 levels. It is found that in age-matched controls, SAC had higher IL-6 levels.

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Figures

Figure 1
Figure 1
Age distribution of 17 children, age less than 18 years old and sexually abused and 10 children who were not abused (control group), according to gender.

References

    1. Criminal Code of the Republic of Turkey. The law no:104. [[Accessed: 2016 November 18]]. Available from: www.tck.gov.tr .
    1. Simsek S, Uysal C, Kaplan I, Yuksel T, Aktas H. BDNF and cortisol levels in children with or without post-traumatic stress disorder after sustaining sexual abuse. Psychoneuroendocrinology. 2015;56:45–51. - PubMed
    1. World Health Organization. Promoting research to prevent child maltreatment [Internet] XIXth ISPCAN International Congress on Child Abuse and Neglect. Geneva (CH): WHO; 2012. [[Accessed:17/11/2016]]. Available from: http://www.who.int/violence_injury_prevention/violence/child/ispscan_rep... .
    1. Groer MW, Thomas SP, Evans GW, Helton S, Weldon A. Inflammatory effects and immune system correlates of rape. Violence Vict. 2006;21:796–808. - PubMed
    1. Oster H, Challet E, Ott V, Arvat E, de Kloet ER, Dijk DJ, et al. The functional and clinical significance of the 24-hour rhythm of circulating glucocorticoids. Endocr Rev. 2017;38:3–45. - PMC - PubMed

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