Ageing-induced internalization and degradation of VE-cadherin leads to vascular dysfunction
- PMID: 29210069
- PMCID: PMC5767686
- DOI: 10.1113/JP275495
Ageing-induced internalization and degradation of VE-cadherin leads to vascular dysfunction
Keywords: ageing; cardiovascular physiology; vascular dysfunction.
Comment on
-
Impaired activity of adherens junctions contributes to endothelial dilator dysfunction in ageing rat arteries.J Physiol. 2017 Aug 1;595(15):5143-5158. doi: 10.1113/JP274189. Epub 2017 Jun 30. J Physiol. 2017. PMID: 28561330 Free PMC article.
Similar articles
-
Impaired activity of adherens junctions contributes to endothelial dilator dysfunction in ageing rat arteries.J Physiol. 2017 Aug 1;595(15):5143-5158. doi: 10.1113/JP274189. Epub 2017 Jun 30. J Physiol. 2017. PMID: 28561330 Free PMC article.
-
CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin in Endothelial Adherens Junctions.Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1098-1114. doi: 10.1161/ATVBAHA.116.308792. Epub 2017 Apr 20. Arterioscler Thromb Vasc Biol. 2017. PMID: 28428220
-
VE-cadherin complex plasticity: EPS8 and YAP play relay at adherens junctions.Tissue Barriers. 2016 Sep 3;4(4):e1232024. doi: 10.1080/21688370.2016.1232024. eCollection 2016. Tissue Barriers. 2016. PMID: 28123926 Free PMC article.
-
Beyond vessels: occurrence and regional clustering of vascular endothelial (VE-)cadherin-containing junctions in non-endothelial cells.Cell Tissue Res. 2009 Jan;335(1):49-65. doi: 10.1007/s00441-008-0718-1. Epub 2008 Nov 11. Cell Tissue Res. 2009. PMID: 19002500 Review.
-
VE-cadherin in vascular development: a coordinator of cell signaling and tissue morphogenesis.Curr Top Dev Biol. 2015;112:325-52. doi: 10.1016/bs.ctdb.2014.11.024. Epub 2015 Feb 11. Curr Top Dev Biol. 2015. PMID: 25733145 Review.
References
-
- Lee M‐J, Thangada S, Claffey KP, Ancellin N, Liu CH, Kluk M, Volpi M, Sha'afi RI & Hla T (1999). Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine‐1‐phosphate. Cell 99, 301–312. - PubMed
-
- Orsenigo F, Giampietro C, Ferrari A, Corada M, Galaup A, Sigismund S, Ristagno G, Maddaluno L, Young Koh G, Franco D, Kurtcuoglu V, Poulikakos D, Baluk P, McDonald D, Grazia Lampugnani M & Dejana E (2012). Phosphorylation of VE‐cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo. Nat Commun 3, 1208. - PMC - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical