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Comment
. 2017 Dec 5;26(6):805-806.
doi: 10.1016/j.cmet.2017.11.010.

RevAMPing Mitochondrial Shape to Live Longer

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RevAMPing Mitochondrial Shape to Live Longer

Lena Pernas et al. Cell Metab. .
Free article

Abstract

Whether and how mitochondria connect reduced energy intake to healthy aging are unclear. In this issue of Cell Metabolism, Weir et al. (2017) find that constitutive AMPK activation and dietary restriction promote longevity in C. elegans via remodeling of the mitochondrial network and fatty acid oxidation in peripheral tissues.

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