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. 1989 Feb;42(2):206-9.
doi: 10.1136/jcp.42.2.206.

Biotin-labelled antigen screening test for toxoplasma IgM antibody

A W Joss  1 , L J Skinner, I L Moir, J M Chatterton, H Williams, D O Ho-Yen
Affiliations

Biotin-labelled antigen screening test for toxoplasma IgM antibody

A W Joss et al. J Clin Pathol. 1989 Feb.

Abstract

A method for the simple preparation of biotin-labelled toxoplasma antigen was used with avidin peroxidase in an IgM-capture enzyme linked immunosorbent assay (BAM-ELISA). Although the overall predictive value of a positive result was only 38%, its low cost and 100% sensitivity makes it a very suitable screening test. Positive results can be confirmed by an alternative assay, thus providing a more economical and effective diagnostic service than either screening all sera by a commercial test or selecting sera for IgM testing.

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