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Editorial
. 2017 Nov 17;8(8):1513-1515.
doi: 10.1080/21505594.2017.1415191.

Establishing the critical role of peripheral blood vessel colonisation by Neisseria meningitidis in invasive meningococcal disease

Ronan F O'Toole  1
Affiliations
Editorial

Establishing the critical role of peripheral blood vessel colonisation by Neisseria meningitidis in invasive meningococcal disease

Ronan F O'Toole. Virulence. .

Abstract

In this issue of Virulence, Capel and colleagues describe the use of a unique humanised mouse model to elucidate specific interactions between Neisseria meningitidis and human endothelial cells during blood-borne infection in vivo. Here, a number of the key findings from their study and their implications for our understanding of invasive meningococcal disease are explored.

Keywords: Meningitis; Meningococcaemia; Neisseria meningitidis; Purpura fulminans; Transposon mutagenesis.

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Comment on

  • Peripheral blood vessels are a niche for blood-borne meningococci.
    Capel E, Barnier JP, Zomer AL, Bole-Feysot C, Nussbaumer T, Jamet A, Lécuyer H, Euphrasie D, Virion Z, Frapy E, Pélissier P, Join-Lambert O, Rattei T, Bourdoulous S, Nassif X, Coureuil M. Capel E, et al. Virulence. 2017 Nov 17;8(8):1808-1819. doi: 10.1080/21505594.2017.1391446. Epub 2017 Nov 27. Virulence. 2017. PMID: 29099305 Free PMC article.

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