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Review
. 2018 Jan 10;36(2):144-150.
doi: 10.1200/JCO.2017.75.9845. Epub 2017 Dec 8.

Soft Tissue and Uterine Leiomyosarcoma

Suzanne George  1 , César Serrano  1 , Martee L Hensley  1 , Isabelle Ray-Coquard  1
Affiliations
Review

Soft Tissue and Uterine Leiomyosarcoma

Suzanne George et al. J Clin Oncol. .

Abstract

Leiomyosarcoma (LMS) is one of the most common subtypes of soft tissue sarcoma in adults and can occur in almost any part of the body. Uterine leiomyosarcoma is the most common subtype of uterine sarcoma. Increased awareness of this unique histology has allowed for the development of drugs that are specific to LMS and has begun to shed light on the similarities and possible unique aspects of soft tissue and uterine LMS. In this review, we summarize the current understanding of the epidemiology, diagnosis, genomics, and treatment options for LMS.

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