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. 2017 Jan 1:2017:bax040.
doi: 10.1093/database/bax040.

Triage by ranking to support the curation of protein interactions

Luc Mottin  1   2 , Emilie Pasche  1   2 , Julien Gobeill  1   2 , Valentine Rech de Laval  3   4 , Anne Gleizes  3 , Pierre-André Michel  3 , Amos Bairoch  3   4 , Pascale Gaudet  3   4 , Patrick Ruch  1   2
Affiliations

Triage by ranking to support the curation of protein interactions

Luc Mottin et al. Database (Oxford). .

Abstract

http://candy.hesge.ch/nextA5.

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Figures

Figure 1.
Figure 1.
Comparison of the precision at P0 for the PPIs and PTMs ranking task by using PubMed versus BioMed, neXtA5 and neXtA5 augmented with the query refinement approach.
Figure 2.
Figure 2.
Architecture of the neXtA5 implementation in the BioEditor.
Figure 3.
Figure 3.
Phase 2, selection of a relevant publication in the ranked list.
Figure 4.
Figure 4.
Phase 3, curation of the proposed annotations.
See this image and copyright information in PMC

References

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    1. Jones S., Thornton J.M. (1996) Principles of protein-protein interactions. Proc. Natl. Acad. Sci. USA, 93, 13–20. - PMC - PubMed
    1. Cusick M.E., Klitgord N., Vidal M.. et al. (2005) Interactome: gateway into systems biology. Hum. Mol. Genet., 14, 171–181. - PubMed
    1. Khoury G.A., Baliban R.C., Floudas C.A. (2011) Proteome-wide post-translational modification statistics: frequency analysis and curation of the Swiss-Prot database. Sci. Rep., 1, 90(doi:10.1038/srep00090. - PMC - PubMed
    1. Alberts B., Johnson A., Lewis J.. et al. (2008) Molecular biology of the cell, 5th Edition. New York: Garland Science, 5th edn. ISBN-13: 978-0815341062.

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