Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Jan 1:2017:bax041.
doi: 10.1093/database/bax041.

TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species

Sony Malhotra  1 , Grace Mugumbate  1 , Tom L Blundell  1 , Alicia P Higueruelo  1
Affiliations

TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species

Sony Malhotra et al. Database (Oxford). .

Abstract

http://www-cryst.bioc.cam.ac.uk/tible/.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Snapshot of the TIBLE database highlighting the type of data stored for mycobacterial species.
Figure 2.
Figure 2.
(A) MIC data points for Mycobacterium tuberculosis extracted from the ChEMBL and Collaborative Drug Discovery databases. (B) Small molecule binding data mapped to the target protein-Rv1484 in Mycobacterium tuberculosis. This page provides a link to the available protein structures in the PDB for this target protein, protein structure models in CHOPIN database and also the off-target predictions using the ligand-based methods.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. WHO. (2016) Global Tuberculosis Report 2016.
    1. WHO. (2015) Global tuberculosis report 2015.
    1. Gaulton A., Hersey A., Nowotka M.. et al. (2016) The ChEMBL database in 2017. Nucleic Acids Res., 45, D945–D954. - PMC - PubMed
    1. Law V., Knox C., Djoumbou Y.. et al. (2014) DrugBank 4.0: shedding new light on drug metabolism. Nucleic Acids Res., 42, D1091–D1097. - PMC - PubMed
    1. Kim S., Thiessen P.A., Bolton E.E.. et al. (2016) PubChem Substance and Compound databases. Nucleic Acids Res., 44, D1202–D1213. - PMC - PubMed

Publication types

MeSH terms

LinkOut - more resources