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Meta-Analysis
. 2018 Apr;12(2):256-267.
doi: 10.1007/s11764-017-0665-5. Epub 2017 Dec 8.

Tai Chi and Qigong for cancer-related symptoms and quality of life: a systematic review and meta-analysis

Peter M Wayne  1 , M S Lee  2 , J Novakowski  3 , K Osypiuk  3 , J Ligibel  4 , L E Carlson  5 , R Song  6
Affiliations
Meta-Analysis

Tai Chi and Qigong for cancer-related symptoms and quality of life: a systematic review and meta-analysis

Peter M Wayne et al. J Cancer Surviv. 2018 Apr.

Abstract

Purpose: This study aims to summarize and critically evaluate the effects of Tai Chi and Qigong (TCQ) mind-body exercises on symptoms and quality of life (QOL) in cancer survivors.

Methods: A systematic search in four electronic databases targeted randomized and non-randomized clinical studies evaluating TCQ for fatigue, sleep difficulty, depression, pain, and QOL in cancer patients, published through August 2016. Meta-analysis was used to estimate effect sizes (ES, Hedges' g) and publication bias for randomized controlled trials (RCTs). Methodological bias in RCTs was assessed.

Results: Our search identified 22 studies, including 15 RCTs that evaluated 1283 participants in total, 75% women. RCTs evaluated breast (n = 7), prostate (n = 2), lymphoma (n = 1), lung (n = 1), or combined (n = 4) cancers. RCT comparison groups included active intervention (n = 7), usual care (n = 5), or both (n = 3). Duration of TCQ training ranged from 3 to 12 weeks. Methodological bias was low in 12 studies and high in 3 studies. TCQ was associated with significant improvement in fatigue (ES = - 0.53, p < 0.001), sleep difficulty (ES = - 0.49, p = 0.018), depression (ES = - 0.27, p = 0.001), and overall QOL (ES = 0.33, p = 0.004); a statistically non-significant trend was observed for pain (ES = - 0.38, p = 0.136). Random effects models were used for meta-analysis based on Q test and I 2 criteria. Funnel plots suggest some degree of publication bias. Findings in non-randomized studies largely paralleled meta-analysis results.

Conclusions: Larger and methodologically sound trials with longer follow-up periods and appropriate comparison groups are needed before definitive conclusions can be drawn, and cancer- and symptom-specific recommendations can be made.

Implications for cancer survivors: TCQ shows promise in addressing cancer-related symptoms and QOL in cancer survivors.

Keywords: Cancer; Fatigue; Meta-analysis; Qigong; Quality of life; Tai Chi.

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Figures

Figure 1
Figure 1
Summary of the flow of our literature search according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines.
Figure 2
Figure 2
Effects of Tai Chi/Qigong on cancer-related symptoms and quality of life Note. Data presented included weighted contribution, effect size (Hedges g) and confidence interval of LL (lower limit) to UL (upper limit) of each study.
Figure 2
Figure 2
Effects of Tai Chi/Qigong on cancer-related symptoms and quality of life Note. Data presented included weighted contribution, effect size (Hedges g) and confidence interval of LL (lower limit) to UL (upper limit) of each study.
See this image and copyright information in PMC

References

    1. Society AC. Book Cancer treatment and survivorship facts and figures 2016–2017. City: American Cancer Society; 2016. Cancer treatment and survivorship facts and figures 2016–2017.
    1. Loscalzo M, Clark K, Pal S, Pirl WF. Role of biopsychosocial screening in cancer care. Cancer J. 2013;19:414–420. - PubMed
    1. Novy DM, Aigner CJ. The biopsychosocial model in cancer pain. Curr Opin Support Palliat Care. 2014;8:117–123. - PubMed
    1. Richtig E, Trapp M, Kapfhammer HP, Jenull B, Richtig G, Trapp EM. The Importance of a Biopsychosocial Approach in Melanoma ResearchExperiences from a Single-center Multidisciplinary Melanoma Working Group in Middle-Europe. Acta Derm Venereol. 2016;96:51–54. - PubMed
    1. Chaoul A, Milbury K, Sood AK, Prinsloo S, Cohen L. Mind-body practices in cancer care. Curr Oncol Rep. 2014;16:417. - PMC - PubMed

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