doi: 10.1007/978-1-4939-7571-6_12.
Oligodendrocyte Progenitor Cell Cultures: A Model to Screen Neurotrophic Compounds for Myelin Repair
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- PMID: 29222780
- DOI: 10.1007/978-1-4939-7571-6_12
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Oligodendrocyte Progenitor Cell Cultures: A Model to Screen Neurotrophic Compounds for Myelin Repair
Methods Mol Biol.
2018.
Abstract
The protocol presented in this chapter covers the application of rat cortical oligodendrocyte progenitor cells cultured under conditions of differentiation for the evaluation of agents with potential trophic activity, that is, which are capable of promoting maturation under such conditions. As an example we have chosen a co-ultramicronized N-palmitoylethanolamine/luteolin composite, a formulation described in the literature as possessing anti-inflammatory, neuroprotective, and neuroregenerative actions.
Keywords: Cell culture; Cortex; Differentiation; Myelin; Oligodendrocytes; Progenitor; Rat.
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