You Have Brains in Your Head, You Have Organoids in Your Dish, You Can Steer Yourself in any Direction You Wish
- PMID: 29225549
- PMCID: PMC5716505
- DOI: 10.5698/1535-7597.17.5.311
You Have Brains in Your Head, You Have Organoids in Your Dish, You Can Steer Yourself in any Direction You Wish
Comment on
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Induction of Expansion and Folding in Human Cerebral Organoids.Cell Stem Cell. 2017 Mar 2;20(3):385-396.e3. doi: 10.1016/j.stem.2016.11.017. Epub 2016 Dec 29. Cell Stem Cell. 2017. PMID: 28041895 Free PMC article.
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Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia.Cell Stem Cell. 2017 Apr 6;20(4):435-449.e4. doi: 10.1016/j.stem.2016.12.007. Epub 2017 Jan 19. Cell Stem Cell. 2017. PMID: 28111201 Free PMC article.
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Assembly of functionally integrated human forebrain spheroids.Nature. 2017 May 4;545(7652):54-59. doi: 10.1038/nature22330. Epub 2017 Apr 26. Nature. 2017. PMID: 28445465 Free PMC article.
References
-
- Grone BP, Baraban SC.. Animal models in epilepsy research: legacies and new directions. Nat Neurosci 2015; 18: 339– 343. - PubMed
-
- Kato M, Dobyns WB.. Lissencephaly and the molecular basis of neuronal migration. Hum Mol Genet 2003; 12: R89– R96. - PubMed
-
- Hansen DV, Lui JH, Parker PR, Kriegstein AR.. Neurogenic radial glia in the outer subventricular zone of human neocortex. Nature 2010; 464: 554– 561. - PubMed
-
- Mirzaa GM, Poduri A.. Megalencephaly and hemimegalencephaly: breakthroughs in molecular etiology. Am J Med Genet C Semin Med Genet 2014; 166C: 156– 172. - PubMed
-
- Birely F, Andersen J, Makinson CS, Islam S, Wei W, Huber N, Fan HC, Metzler KRC, Panagiotakos G, Thom N, O'Rourke NA, Steinmetz LM, Berstein JA, Hallmayer J, Huguenard JR, Pasca SP.. Assembly of functionally integrated human forebrain spheroids. Nature 2017; 545: 54– 59. doi: 10.1038/nature22330 - PMC - PubMed
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