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Editorial
. 2017 May 22;4(1):e000617.
doi: 10.1136/openhrt-2017-000617. eCollection 2017.

Decreased magnesium status may mediate the increased cardiovascular risk associated with calcium supplementation

James J DiNicolantonio  1 , Mark F McCarty  2 , James H O'Keefe  1
Affiliations
Editorial

Decreased magnesium status may mediate the increased cardiovascular risk associated with calcium supplementation

James J DiNicolantonio et al. Open Heart. .
No abstract available

Keywords: absorption; calcitriol; calcium supplementation; magnesium; vascular events.

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Conflict of interest statement

Competing interests: JHO: Chief Medical Officer and Founder of CardioTabs, a nutraceutical company, have a major ownership interest in the company. CardioTabs does sell products that contain Omega-3. MFM: owner and science director of NutriGuard Research, a nutraceutical company. A few of NutriGuard’s products contain calcium and/or magnesium.

Figures

Figure 1
Figure 1
Adjusted odds of prevalent or high CAC and AAC according to self-reported total (dietary and supplemental) magnesium intake. Data from Hruby et al.56
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References

    1. Bolland MJ, Grey A, Avenell A, et al. . Calcium supplements with or without vitamin D and risk of cardiovascular events: reanalysis of the Women’s Health Initiative limited access dataset and meta-analysis. BMJ 2011;342:d2040 10.1136/bmj.d2040 - DOI - PMC - PubMed
    1. Xiao Q, Murphy RA, Houston DK, et al. . Dietary and supplemental calcium intake and cardiovascular disease mortality: the National Institutes of Health-AARP diet and health study. JAMA Intern Med 2013;173:639–46. 10.1001/jamainternmed.2013.3283 - DOI - PMC - PubMed
    1. Li K, Kaaks R, Linseisen J, et al. . Associations of dietary calcium intake and calcium supplementation with myocardial infarction and stroke risk and overall cardiovascular mortality in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition study (EPIC-Heidelberg). Heart 2012;98:920–5. 10.1136/heartjnl-2011-301345 - DOI - PubMed
    1. Anderson JJ, Kruszka B, Delaney JA, et al. . Calcium intake from diet and supplements and the risk of coronary artery calcification and its progression among older adults: 10‐year follow‐up of the Multi-Ethnic Study of Atherosclerosis (MESA). J Am Heart Assoc 2016;5:e003815 10.1161/JAHA.116.003815 - DOI - PMC - PubMed
    1. Wang L, Manson JE, Sesso HD. Calcium intake and risk of cardiovascular disease: a review of prospective studies and randomized clinical trials. Am J Cardiovasc Drugs 2012;12:105–16. 10.2165/11595400-000000000-00000 - DOI - PMC - PubMed

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