Evolution of virulence in Enterococcus faecium, a hospital-adapted opportunistic pathogen
- PMID: 29227922
- DOI: 10.1016/j.mib.2017.11.030
Evolution of virulence in Enterococcus faecium, a hospital-adapted opportunistic pathogen
Abstract
Enterococci are long-standing members of the human microbiome and they are also widely distributed in nature. However, with the surge of antibiotic-resistance in recent decades, two enterococcal species (Enterococcus faecalis and Enterococcus faecium) have emerged to become significant nosocomial pathogens, acquiring extensive antibiotic resistance. In this review, we summarize what is known about the evolution of virulence in E. faecium, highlighting a specific clone of E. faecium called ST796 that has emerged recently and spread globally.
Copyright © 2017 Elsevier Ltd. All rights reserved.
Comment in
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Editorial overview: Host-pathogen interactions shaped through evolutionary and regulatory processes.Curr Opin Microbiol. 2018 Feb;41:v-viii. doi: 10.1016/j.mib.2018.02.001. Curr Opin Microbiol. 2018. PMID: 29559085 No abstract available.
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