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Review
. 2018 Mar;26(3):319-325.
doi: 10.1016/j.joca.2017.11.014. Epub 2017 Dec 8.

Osteoarthritis year in review 2017: clinical

Affiliations
Review

Osteoarthritis year in review 2017: clinical

A E Nelson. Osteoarthritis Cartilage. 2018 Mar.

Abstract

This review is based on a systematic review of the literature relevant to clinical topics in osteoarthritis (OA) performed for the time period February 22, 2016 to April 1, 2017. A PubMed search using the terms "osteoarthritis" and "treatment or epidemiology" returned over 800 papers, of which 57 are reviewed here, with inclusion primarily based on relevance to clinical OA. Epidemiologic studies in this time frame focused on the incidence and prevalence of OA, comorbidities and mortality in relation to OA (particularly obesity and cardiovascular disease), and multiple joint involvement. Papers on therapeutic approaches to OA considered: non-pharmacologic options, a number of topical, oral, and intra-articular therapies, as well as the cost-effectiveness of some OA treatments. There an enormous need to identify novel strategies to reduce the impact of this highly prevalent and debilitating condition.

Keywords: Epidemiology; Osteoarthritis; Systematic review; Treatment.

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Conflict of interest statement

Competing interest statement

The author is a consultant to GSK, has received honoraria for online presentations on MedScape and QuantiaMD, book royalties from Health Press, Ltd., and has received grant funding from NIH/NIAMS, CDC, and the Rheumatology Research Foundation. This review represents the opinion of the author and does not reflect the official view of these or any other agencies.

Figures

Figure
Figure
Flowchart of search strategy and manuscript inclusion

References

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