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Practice Guideline
. 2018 Jan;20(1):89-96.
doi: 10.1007/s12094-017-1807-y. Epub 2017 Dec 11.

SEOM clinical guideline on unknown primary cancer (2017)

F Losa  1 , G Soler  2 , A Casado  3 , A Estival  4 , I Fernández  5 , S Giménez  6 , F Longo  7 , R Pazo-Cid  8 , J Salgado  9 , M Á Seguí  10
Affiliations
Practice Guideline

SEOM clinical guideline on unknown primary cancer (2017)

F Losa et al. Clin Transl Oncol. 2018 Jan.

Abstract

Cancer of unknown primary site is a histologically confirmed cancer that manifests in advanced stage, with no identifiable primary site following standard diagnostic procedures. Patients are initially categorized based on the findings of the initial biopsy: adenocarcinoma, squamous-cell carcinoma, neuroendocrine carcinoma, and poorly differentiated carcinoma. Appropriate patient management requires understanding several clinical and pathological features that aid in identifying several subsets of patients with more responsive tumors.

Keywords: Cancer; Chemotherapy; Diagnosis and treatment; Unknown primary site.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
A stepwise algorithm with IHC staining should be applied to assess CUP specimens
See this image and copyright information in PMC

References

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