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Editorial
. 2018;17(4):393-394.
doi: 10.1080/15384101.2017.1414682. Epub 2018 Feb 9.

Functional regulation of proteins by 20S proteasome proteolytic processing

Maya A Olshina  1 , Gili Ben-Nissan  1 , Michal Sharon  1
Affiliations
Editorial

Functional regulation of proteins by 20S proteasome proteolytic processing

Maya A Olshina et al. Cell Cycle. 2018.
No abstract available

Keywords: 20S proteasome; functional regulation; intrinsically disordered proteins; post-translational processing; protein degradation.

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Figures

Figure 1.
Figure 1.
The 20S proteasome is capable of cleaving substrates leading to either full proteolysis of the unfolded substrate into small peptides, or to selective proteolysis of a specific disordered region within the polypeptide chain. The latter may lead to the generation of a degradation product that retains structural elements and has a differential functional property.
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References

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