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. 2018 Oct;32(20):2392-2397.
doi: 10.1080/14786419.2017.1413572. Epub 2017 Dec 13.

Chemical constituents from the fruiting bodies of Phellinus igniarius

Nguyen Tan Thanh  1 , Nguyen Ngoc Tuan  2 , Ping-Chung Kuo  3 , Doan Manh Dung  4 , Doan Lan Phuong  5 , Dinh Thi Truong Giang  6 , Tian-Shung Wu  3   7 , Tran Dinh Thang  1
Affiliations

Chemical constituents from the fruiting bodies of Phellinus igniarius

Nguyen Tan Thanh et al. Nat Prod Res. 2018 Oct.

Abstract

A new tirucallane-type triterpenoid igniarine (1), and four known compounds meshimakobnol A (2), meshimakobnol B (3), ergosterol (4) and ergosterol peroxide (5), were purified from the methanol extracts of the fruiting bodies of Phellinus igniarius (DC. ex Fr.) Quél. The structure of 1 was elucidated using a combination of 1D and 2D NMR techniques and HR-ESI-MS analyses. In addition, the isolated compounds were examined for their cytotoxicity against several tumour cell lines and part of the tested compounds demonstrated weak cytotoxicity.

Keywords: Hymenochaetaceae; Phellinus igniarius; cytotoxicity; igniarine.

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