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Comment
. 2017 Dec 19;114(51):E10859-E10860.
doi: 10.1073/pnas.1718429115. Epub 2017 Dec 12.

Reply to Mohlin et al.: High levels of EPAS1 are closely associated with key features of low-risk neuroblastoma

Isabelle Westerlund  1 , Yao Shi  1 , Konstantinos Toskas  1 , Stuart M Fell  1 , Shuijie Li  1   2 , Erik Södersten  1 , Susanne Schlisio  1   2 , Johan Holmberg  3
Affiliations
Comment

Reply to Mohlin et al.: High levels of EPAS1 are closely associated with key features of low-risk neuroblastoma

Isabelle Westerlund et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

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References

    1. Westerlund I, et al. Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression. Proc Natl Acad Sci USA. 2017;114:E6137–E6146. - PMC - PubMed
    1. Mohlin S, et al. No reason to reconsider HIF-2 as an oncogene in neuroblastoma and other cancer forms. Proc Natl Acad Sci USA. 2017 doi: 10.1073/pnas.1716644115. - DOI - PMC - PubMed
    1. Qing G, et al. Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha. Cancer Res. 2010;70:10351–10361. - PMC - PubMed
    1. Mohlin S, Hamidian A, Påhlman S. HIF2A and IGF2 expression correlates in human neuroblastoma cells and normal immature sympathetic neuroblasts. Neoplasia. 2013;15:328–334. - PMC - PubMed
    1. Holmquist-Mengelbier L, et al. Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype. Cancer Cell. 2006;10:413–423. - PubMed

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