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. 2017 Dec 8:12:34.
doi: 10.1186/s12995-017-0181-6. eCollection 2017.

Vibration thresholds in carpal tunnel syndrome assessed by multiple frequency vibrometry: a case-control study

Magnus Flondell  1   2 , Birgitta Rosén  1   2 , Gert Andersson  3   4 , Tommy Schyman  5 , Lars B Dahlin  1   2 , Anders Björkman  1   2
Affiliations

Vibration thresholds in carpal tunnel syndrome assessed by multiple frequency vibrometry: a case-control study

Magnus Flondell et al. J Occup Med Toxicol. .

Abstract

Background: Carpal tunnel syndrome (CTS) is the most common compression neuropathy, but there is no gold standard for establishing the diagnosis. The ability to feel vibrations in the fingertips is dependent on the function in cutaneous receptors and afferent nerves. Our aim was to investigate vibration perception thresholds (VPTs) in patients with CTS using multi-frequency vibrometry.

Methods: Sixty-six patients (16 men and 50 women) with CTS, diagnosed from clinical signs and by electroneurography, and 66 matched healthy controls were investigated with multi-frequency vibrometry. The VPTs were assessed at seven frequencies (8, 16, 32, 64, 125, 250, and 500 Hz) in the index finger and little finger bilaterally. The severity of the CTS was graded according to Padua and the patient's subjective symptoms were graded according to the Boston carpal tunnel questionnaire. Touch thresholds were assessed using the Semmes-Weinstein monofilaments.

Results: Patients with CTS had significantly higher VPTs at all frequencies in the index finger and in 6 out of 7 frequencies in the little finger compared to the controls. However, the VPT was not worse in patients with more severe CTS. Patients with unilateral CTS showed significantly higher VPTs in the affected hand. There were no correlations between VPTs and electrophysiological parameters, subjective symptoms, or touch threshold.

Conclusions: Patients with CTS had impaired VPTs at all frequencies compared to the controls. Since the VPTs are dependent on function in peripheral receptors and their afferent nerves, multi-frequency vibrometry could possibly lead to diagnosis of CTS.

Keywords: Carpal tunnel syndrome; Sensibility; Touch thresholds; Vibration perception threshold; Vibrometry; Vibrotactile sense.

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Conflict of interest statement

Ethics approval and consent to participate

This study and the cohort study from which the healthy controls were identified were approved by the ethical committee of Lund University (nos. 269–2008 and 386–2007). Both studies were conducted according to the tenets of the Declaration of Helsinki. All the participants gave their written consent.

Consent for publication

Consent for publication was obtained.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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