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Comment
. 2018 Jan;26(1):4-5.
doi: 10.1016/j.tim.2017.11.009. Epub 2017 Nov 24.

Modelling the Kinetic Response to Nutrient Fluctuations

Marco Fondi  1
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Modelling the Kinetic Response to Nutrient Fluctuations

Marco Fondi. Trends Microbiol. 2018 Jan.

Abstract

Understanding and predicting how microbes respond to environmental fluctuations is a central challenge in present-day microbiology. Erickson et al. have proposed a quantitative and (kinetic) parameters-free model of Escherichia coli growth that successfully anticipates changes in gene expression and biomass accumulation in response to nutrients up- and down-shifts.

Keywords: bacterial adaptation; flux controlled regulation model; proteome allocation model.

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