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. 2018 Apr;22(4):1096-1099.
doi: 10.1007/s10461-017-2009-x.

HIV Pre-exposure Prophylaxis (PrEP) Uptake and Retention Among Men Who Have Sex with Men in a Community-Based Sexual Health Clinic

J Carlo Hojilla  1 , David Vlahov  2 , Pierre-Cedric Crouch  3 , Carol Dawson-Rose  4 , Kellie Freeborn  4   3 , Adam Carrico  5
Affiliations

HIV Pre-exposure Prophylaxis (PrEP) Uptake and Retention Among Men Who Have Sex with Men in a Community-Based Sexual Health Clinic

J Carlo Hojilla et al. AIDS Behav. 2018 Apr.

Abstract

In a community-based clinic serving men who have sex with men in San Francisco, California, this study characterized key steps of the pre-exposure prophylaxis (PrEP) cascade and identified correlates of retention in care. In total, 344 patients were evaluated for PrEP. Three-fourths (78%) of those who sought PrEP services initiated PrEP. The overall cumulative incidence of discontinuing PrEP at 13 months was 38%. Men with a sexually transmitted infection (STI) were 44% less likely to be retained (adjusted hazard ratio [aHR] 0.56, 95% confidence interval [0.33-0.95]). Comprehensive retention efforts for men with STIs are crucial to optimize the benefits of PrEP.

Keywords: HIV pre-exposure prophylaxis; Men who have sex with men; PrEP; PrEP cascade; Retention in care.

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Figures

Figure 1
Figure 1
The pre-exposure prophylaxis (PrEP) cascade at a nurse-led community-based sexual health clinic serving men who have sex with men (MSM). Patients were followed up to 488 days from enrollment. Of those who sought PrEP services, 268 (78%) initiated PrEP. Cost was the most commonly cited reason for not starting PrEP. Among those who initiated PrEP, 127 (47%) were retained in the program at the end of follow-up.
See this image and copyright information in PMC

References

    1. Nunn AS, Brinkley-Rubinstein L, Oldenburg CE, Mayer KH, Mimiaga M, Patel R, et al. Defining the HIV pre-exposure prophylaxis care continuum. AIDS. 2017 Mar;31:731–4. - PMC - PubMed
    1. Parsons JT, Rendina HJ, Lassiter JM, Whitfield THF, Starks TJ, Grov C. Uptake of HIV pre-exposure prophylaxis (PrEP) in a national cohort of gay and bisexual men in the United States. J Acquir Immune Defic Syndr. 2017 Mar 1;74(3):285–92. - PMC - PubMed
    1. Volk JE, Marcus JL, Phengrasamy T, Blechinger D, Nguyen DP, Follansbee S, et al. No new HIV infections withincreasing use of HIV preexposure prophylaxis in a clinical practice setting. Clin Infect Dis. 2015 Nov 15;61(10):1601–3. - PMC - PubMed
    1. Chan PA, Mena L, Patel R, Oldenburg CE, Beauchamps L, Perez-Brumer AG, et al. Retention in care outcomes for HIV pre-exposure prophylaxis implementation programmes among men who have sex with men in three US cities. J Int AIDS Soc. 2016 Jun;19(1):20903. - PMC - PubMed
    1. Carrico AW, Riley ED, Johnson MO, Charlebois ED, Neilands TB, Remien RH, et al. Psychiatric risk factors for HIV disease progression: the role of inconsistent patterns of antiretroviral therapy utilization. J Acquir Immune Defic Syndr. 2011 Feb;56:146–50. - PMC - PubMed

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